Department of Molecular Biosciences
Dr. He obtained his Bachelor’s degree from Beijing Technology and Business University in China and Ph.D. from Northwestern University. After doing a post-doctoral research with Eva Nogales at Berkeley, California, Dr. He returned to Northwestern University as an assistant professor to set up his independent lab. His lab is interested in studying the molecular mechanisms by which large, multi-subunit complexes engage in DNA-centric processes. Current research topics include two main area: (1) how gene transcription is regulated by the assembly of the initiation complex at the core promoter and (2) how various types of DNA damage are repaired and why deficiencies in these repair pathways lead to pathology of cancer predisposition or accelerated aging.